Forecast Ledgerinterventional psychiatry and psychedelic medicineQuoted, dated predictions scored against public outcomes under one written method. Every score links to the words, the rule and the evidence.

Not admitted · Not a forecast

Rules 1.1.0 · as of 14 Sep 2026

Owen Scott Muir · Said 17 Mar 2025 · owen-1662

Quote

Not a forecast

“It's possible, for example, that there is inflammatory depression as a subtype that might be relevant for whether someone will respond to transcranial magnetic stimulation as delivered in this setting”
· Is Depression An Immune-Mediated Disease? · substack post

Discussion of Koparal et al. (2025), a retrospective study of 86 treatment-resistant depression patients at Gazi University (Ankara) that links a high neutrophil-lymphocyte ratio (NLR) to non-response to 10 Hz rTMS. The author floats the hypothesis that an inflammatory depression subtype exists and could predict who responds to rTMS.

Descriptive, retrospective, or a statement of preference; no future state asserted.

← Earlier · Later → · All statements