Forecast Ledgerinterventional psychiatry and psychedelic medicineQuoted, dated predictions scored against public outcomes under one written method. Every score links to the words, the rule and the evidence.

Not admitted · Third-party claim

Rules 1.1.0 · as of 14 Sep 2026

Quote

Third-party claim

“This is why Janssen, the manufacturer, is still making huge profits from a simple enantiomer—on track for $2b this year.”
· Does One Negative Study Ruin Ketamine For Psychiatry? · substack post

Guest section by a reader, 'Dr. MS', a psychiatrist with bipolar disorder, analyzing the KARMA-Dep 2 ketamine vs midazolam trial (JAMA Psychiatry). He argues IV ketamine beats intranasal esketamine but is generic, so Janssen keeps profiting from Spravato, which he says is on track for $2 billion in sales in 2025.

A quoted or paraphrased claim by someone else that the author does not adopt as their own.