Forecast Ledgerinterventional psychiatry and psychedelic medicineQuoted, dated predictions scored against public outcomes under one written method. Every score links to the words, the rule and the evidence.

Not admitted · Normative

Rules 1.1.0 · as of 14 Sep 2026

Owen Scott Muir · Said 22 May 2023 · owen-0505

Quote

Normative

“Nobody should ever do this anymore”
· Antipsychotics Should Never be Used For Augmentation In Depression Anymore · substack post

Thesis of the post (2023-05-22, 'Live from APA'): antipsychotic augmentation of antidepressants (aripiprazole, quetiapine, brexpiprazole are FDA-approved for it) should stop because of weight gain, metabolic risk, tardive dyskinesia and small effect size.

'Should', 'must', 'ought to', 'needs to' with no predictive reading.

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